体外冲击波碎石术联合盐酸坦索罗辛缓释胶囊治疗泌尿结石的效果分析

Effect Analysis of Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Hydrochloride Sustained Release Capsule for Urinary Calculi

目的:探讨体外冲击波碎石术(ESWL)联合盐酸坦索罗辛缓释胶囊用于泌尿结石患者治疗的临床效果。方法:选取2017年4月-2018年5月本院收治的86例泌尿结石患者分为两组,参照组(n=43)仅行ESWL治疗,研究组(n=43)行ESWL治疗后再口服盐酸坦索罗辛缓释胶囊,观察两组排石情况、并发症发生情况等。结果:研究组镇痛药物使用率4.65%、再次发生绞痛率6.98%均明显低于参照组18.60%、23.26%,研究组排石成功率90.70%、总有效率95.35%均明显高于参照组72.09%、81.40%,差异均有统计学意义(P<0.05);研究组平均排石时间明显短于参照组,差异有统计学意义(P<0.05);两组术后并发症发生情况比较,差异无统计学意义(P>0.05)。结论:给予泌尿结石患者体外冲击波碎石术治疗后,再使用盐酸坦索罗辛缓释胶囊,可有效减少镇痛药物使用,降低绞痛再次发生率,提高排石成功率,获得更理想总体疗效,且不会引发严重药物不良反应。

Objective:To investigate the clinical effect of extracorporeal shock wave lithotripsy(ESWL) combined with Tamsulosin Hydrochloride Sustained Release Capsules in the treatment of urinary calculi. Method:86 patients with urinary calculi admitted to our hospital from April 2017 to May 2018 were selected and divided into two groups.The reference group(n=43)was treated with ESWL only.The study group(n=43)was treated with ESWL and then oral Tamsulosin Hydrochloride Sustained Release Capsules.The stone discharge, complications and et al of two groups were observed.Result:The usage rate of analgesic drugs(4.65%)and recurrence rate of colic(6.98%)in the study group were significantly lower than those in the reference group (18.60%,23.26%),the stone removal success rate(90.70%)and total effective rate(95.35%)in the study group were significantly higher than those in the reference group(72.09%,81.40%),the differences were statistically significant(P<0.05).The average stone removal time in the study group was significantly lower than that in the reference group(P<0.05).There was no significant difference in postoperative complications between the two groups(P>0.05).Conclusion:The use of Tamsulosin Hydrochloride Sustained Release Capsules after extracorporeal shock wave lithotripsy for urolithiasis patients can effectively reduce the use of analgesic drugs, reduce the reoccurrence rate of colic,improve the success rate of stone removal,obtain a more ideal overall curative effect,and will not cause serious adverse drug reactions.