不同方式促宫颈成熟后对分娩结局的影响研究

Effect of Different Ways of Promoting Cervical Ripening on Delivery Outcome

目的探讨不同方式促宫颈成熟后对分娩结局的影响。方法选取2017年7月～2018年9月期间本院收治的延期孕产妇中选择114例作为研究对象,根据不同的促宫颈成熟方式将其分为A、B、C三组,每组38例,分别采用普贝生、米索前列醇、催产素引产,评估三组孕产妇的临床效果。结果促宫颈成熟效果:A组有效35例、B组27例、C组23例,A组与B组、C组比较差异显著(P <0.05);分娩结局:A组引产成功率、自然分娩率高于B组与C组;剖宫产率低于B组与C组;用药到临床时间和产程均短于B组与C组(P <0.05);不良反应:三组没有显著差异(P>0.05)。结论在延期孕产妇中应用普贝生引产,效果要优于米索前列醇和催产素,有助于产妇引产成功,能够提高自然分娩率,而且安全性高,可作为首选促宫颈成熟药物予以应用。

Objective To explore the influence of different ways to promote cervical ripening on delivery outcome. Methods 114 cases of delayed pregnant and lying-in women admitted to our hospital from July 2017 to September 2018 were selected as the research objects. They were divided into three groups A, B and C according to different ways to promote cervical ripening. 38 cases in each group were induced by Propess, misoprostol and oxytocin respectively to evaluate the clinical effects of the three groups of delayed pregnant and lying-in women. Results The effect of promoting cervical ripening: 35 cases in group A, 27 cases in group B and 23 cases in group C, and the difference between group A, group B and group C was significant (P < 0.05). Delivery outcome: The success rate of induced labor and natural delivery rate in group A were higher than those in group B and group C;Cesarean section rate was lower than that of group B and group C;The clinical time and stage of labor were shorter than those of group B and group C (P < 0.05). Adverse reactions: there was no significant difference among the three groups (P > 0.05). Conclusion The application of Propess for induced labor in delayed pregnant women is better than misoprostol and oxytocin, which is helpful for successful induced labor, can improve the natural delivery rate, and has high safety. It can be used as the first choice of cervical ripening drugs.