微波消融术治疗良性甲状腺结节临床疗效及CRP水平分析

Clinical efficacy and CRP level analysis of microwave ablation for benign thyroid nodules

目的对良性甲状腺结节者应用微波消融手术医治的临床疗效、CRP水平进行分析、比对。方法对本院2016年6月～2018年1月诊治良性甲状腺结节90例患者临床资料加以分析,按照不同医治方案分成两组,将45例行传统开放术医治患者设为对照组,将45例行微波消融手术医治患者设为观察组,对两组临床疗效、CRP水平和并发症进行比对、分析。结果观察组术中出血量比对照组少,且手术用时和住院时间均比对照组短(P <0.05);观察组CRP、TNF-α、IL-6水平和TSH、FT4、FT3均比对照组优(P <0.05);两组总并发症率比较无显著差异(P>0.05)。结论对良性甲状腺结节者应用微波消融手术医治可缩短手术用时,减少出血量和优化CRP等水平,对甲状腺功能损害小,且安全性较高,值得临床应用。

Objective To analyze and compare the clinical efficacy and CRP level of patients with benign thyroid nodules treated with microwave ablation. Methods The clinical data of 90 patients with benign thyroid nodules from June 2016 to January 2018 were analyzed. The patients were divided into two groups according to different treatment plans. 45 patients who were treated with traditional open surgery were set as the control group. 45 patients performed microwave ablation surgery was as the observation group, and the clinical efficacy, CRP level and complications were compared and analyzed. Results The intraoperative blood loss in the observation group was less than that in the control group, and the time of surgery and hospital stay were shorter than the control group (all P < 0.05). The levels of CRP, TNF-α, IL-6 and TSH, FT4 and FT3 in the observation group were better than the control group (P < 0.05);there was no significant difference in the total complication rate between the two groups (P > 0.05). Conclusion Microwave ablation surgery for benign thyroid nodules can shorten the time of surgery, reduce the amount of bleeding and optimize the level of CRP. It has little damage to thyroid function and is safe,which is worthy of clinical application.