清热化瘀汤对缺血性脑卒中急性期患者的治疗研究

Treatment of Acute Ischemic Stroke Patients with Qingre Huayu Decoction

目的研究清热化瘀汤对缺血性脑卒中急性期(CIS)患者水平及日常生活水平的影响。方法选取2013年8月～2015年12月本院收治的CIS患者76人,以数字法随机分成观察组(38例)和对照组(38例),对两组患者给予治疗。对照组患者按西医标准进行规范性治疗;观察组患者在此基础上加入清热化瘀汤,两组治疗时间均为1个月。结果两组患者血脂治疗后均有改善,CHO和TG改善最为显著,同时,治疗后观察组CHO和TG改善更为明显(均P <0.05)。观察组凝血四项各项数据下降均更为显著(均P <0.05)。观察组Hcy和CRP较对照组有更加明显的降低(均P <0.05)。治疗后两组ADL、QLI评分均有改善,而观察组改善更为明显(均P <0.05)。结论 CIS患者在西医基础治疗上合并使用清热化瘀汤,能多靶点发挥作用,疗效显著,改善了患者血脂、凝血功能、Hcy、CRP水平及日常生活水平,能够在临床上应用。

Objective To study the effect of Qingre Huayu Decoction on the level and daily living of patients with acute ischemic stroke (CIS). Methods 76 CIS patients admitted to our hospital from August 2013 to December 2015 were randomly divided into observation group (38 cases) and control group (38 cases) by digital method, and the two groups of patients were treated. Patients in the control group received standard treatment according to western medicine standards. Patients in the observation group were added with Qingre Huayu Decoction on this basis. The treatment time of both groups was 1 month. Results The blood lipid of the two groups of patients improved after treatment. CHO and TG improved most significantly, while CHO and TG in the observation group improved more significantly after treatment (all P < 0.05). The data of four coagulation items in the observation group decreased more significantly (all P < 0.05). Hcy and CRP in the observation group were significantly lower than those in the control group (both P < 0.05). After treatment, ADL and QLI scores in both groups improved, while the improvement in the observation group was more obvious (all P < 0.05). Conclusion CIS patients combined with Qingre Huayu Decoction on the basis of western medicine treatment can play a role in multiple targets, with significant curative effect, improving the blood lipid, coagulation function, Hcy, CRP level and daily living level of patients, which can be applied clinically.