100例性病梅毒患者的外周血检验价值研究

Study on the Value of Peripheral Blood Test in 100 Patients with Syphilis

目的探析性病梅毒患者对其进行外周血检验的诊断价值。方法随机选取2018年1月～2018年12月间本院检验科收治的确诊为早期获得性梅毒患者100例为本实验的观察对象(观察组),并随机选取同期医院接受健康体检的健康者100例作为本实验的对照对象(对照组),0两组研究对象均采集其外周血,进行外周血细胞形态检验和血清免疫细胞因子检测,比较数据结果的差异。结果观察组异型淋巴细胞、白细胞变化和细胞性贫血发生率均显著高于对照组,细胞正常率低于对照组,差异存在统计学意义(P <0.05);观察组血清IL-2和TNFα含量均明显高于对照组,差异存在统计学意义(P <0.05)。结论对性病梅毒患者进行外周血检验的诊断方法快速、简单,通过对血细胞形态和免疫因子的联合检测有利于确诊性病梅毒。

Objective To investigate the diagnostic value of peripheral blood test in patients with syphilis. Methods 100 patients with early-stage acquired syphilis admitted to our hospital from January 2018 to December 2018 were enrolled in this study (observation group), and 100 randomly selected healthy cases who received health checkups at the same time were used as control group in this study. Peripheral blood were collected from both groups of subjects, and then were performed peripheral blood cell morphology test and serum immunocytokine test, and the results of the data were compared. Results The incidence of atypical lymphocytes, leukocyte changes and cell anemia in the observation group were significantly higher than those in the control group. The normal cell rate was lower than that in the control group. The data difference showed statistical significance (P < 0.05). The levels of serum IL-2 and TNFα in the observation group were significantly higher than those of the control group (P < 0.05). Conclusion The diagnostic method of peripheral blood test in patients with syphilis of sexually transmitted diseases is rapid and simple. The combined detection of blood cell morphology and immune factors is conducive to the diagnosis of syphilis.