银-铜/还原氧化石墨烯修饰的玻碳电极测定当归中的阿魏酸

The determination of ferulic acid in Angelica sinensis by glassy carbon electrode modified with silver-copper /reduced graphene oxide

目的探讨阿魏酸在银-铜双金属/还原氧化石墨烯复合材料修饰的玻碳电极上的电化学行为。方法通过置换反应合成银-铜双金属纳米颗粒,以还原氧化石墨烯为载体负载银-铜双金属纳米颗粒并修饰在玻碳电极上,应用差分脉冲伏安法研究当归中阿魏酸的电化学行为。结果阿魏酸在pH 5.96的B-R缓冲溶液中,在银-铜双金属/还原氧化石墨烯修饰的玻碳电极上于0.30 V时产生1个稳定的还原峰,峰电流与阿魏酸浓度在0.103～8.24μmol/L范围内呈良好的线性关系,检测限为0.033μmol/L(S/N=3)。结论阿魏酸在银-铜双金属/还原氧化石墨烯复合材料修饰的玻碳电极上有较好的电化学行为,响应快,灵敏度高,峰形好,可用于测定当归中的阿魏酸。

Objective To investigate the electrochemical behavior of ferulic acid by a glassy carbon electrode modified with silver-copper bimetal/reduced graphene oxide composite (Ag-Cu/rGO).Methods Silver-copper bimetallic nanoparticles (Ag-Cu) were synthesized by the displacement reaction and Ag-Cu was loaded on the reduced graphene oxide (rGO),and then Ag-Cu/rGO was modified on the glassy carbon electrode (GCE) to study the electrochemical behavior of ferulic acid in Angelica sinensis by differential pulse voltammetry.Results Ferulic acid had a stable reduction peak at 0.30 V in pH 5.96 Britton-Robinson buffer solution at the Ag-Cu@rGO/GCE,and the reduction peak current was linear with the ferulic acid concentration in the range of 0.103-8.24 μmol/L,and the detection limit was 0.033 μmol/L ( S/N =3).Conclusion Ferulic acid had good electrochemical behavior at the Ag-Cu@rGO/GCE with fast response,high sensitivity and well peak shape,and the modified electrode can be used to determine ferulic acid in Angelica sinensis .