国内外不同主体对药品不良反应报告的认知、态度与实践研究综述

Review of the Studies on the Knowledge, Attitude and Practice toward Adverse Drug Reactions Reporting among Different Reporting Entity at Home and Abroad

药品不良反应(ADR)自发报告是药物警戒的重要组成部分,然而全球普遍存在漏报现象。通过综述国内外不同ADR报告主体如药品生产企业、药品经营企业、医疗机构、患者(公众)等对ADR报告的认知、态度与实践研究,发掘ADR自发报告的主要制约因素,为改善我国的ADR自发报告工作提供参考。

Though spontaneous reporting of adverse drug reactions(ADR)plays a critical role in pharmacovigilance,the under-reporting phenomenon is common around the world.This paper mainly reviewed the studies on the knowledge,attitude,and practice toward ADR reporting among different reporting entity such as pharmaceutical production enterprises,drug handling enterprises,medical institutions,and patients(publics)at home and abroad,in order to explore the main constraints in ADR spontaneous reporting and to provide references in improving the ADR spontaneous reporting work in our country.