摘要
原发性甲状旁腺功能亢进症(primary hyperparathyroidism,PHPT)是常见的内分泌疾病之一。本文报道1例49岁男性,临床表现为骨痛,辅助检查提示血总钙在正常范围但游离钙水平升高、低磷血症、高甲状旁腺激素(parathyroid hormone,PTH)血症;超声检查甲状腺双叶后方均可见结节,^(99m)Tc甲氧基异丁基异腈甲状旁腺显像(^(99m)Tc MIBI显像)阴性,11C-胆碱PET/CT和超声引导下穿刺结果支持左侧结节为病变甲状旁腺,与手术病理结果相符,手术治愈。同时对PHPT定位诊断相关文献进行复习和总结。
Primary hyperparathyroidism is one of the common endocrine diseases. Here we reported a 49-year-old male with skeletal pain. Laboratory tests showed normal levels of serum total calcium but elevated ionized calcium concentration, hypophosphatemia and increased parathyroid hormone level. The neck ultrasound showed bilateral parathyroid adenomas, but 99m Tc MIBI result was negative. 11 C-Choline PET/CT and PTH level in ultrasound-guided fine-needle aspiration washout fluid both indicated parathyroid lesion on the left side, in accordance with postoperative pathology. After surgery, all symptoms were improved. Literatures about imaging localization of parathyroid adenomas were reviewed.
作者
段晓晔
马婉璐
朱庆莉
霍力
姜艳
李梅
夏维波
邢小平
王鸥
DUAN Xiao-ye;MA Wan-lu;ZHU Qing-li;HUO Li;JIANG Yan;LI Mei;XIA Wei-bo;XING Xiao-ping;WANG Ou(Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China;Department of Ultrasonics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China;Department of Nuclear Medicine)
出处
《中华骨质疏松和骨矿盐疾病杂志》
CSCD
北大核心
2019年第2期172-176,共5页
Chinese Journal Of Osteoporosis And Bone Mineral Research
基金
中国医学科学院医学与健康科技创新工程重大协同创新项目[(CAMS-I2M)2017-I2M-1-001]
国家自然科学基金(81100559)
国家临床重点专科建设项目(WBY2011-873)
