限制性液体复苏在急诊多发伤合并休克患者中的应用效果

Application effect of limited fluid resuscitation in emergency patients with multiple trauma and shock

目的观察限制性液体复苏在急诊多发伤合并休克患者中的应用效果。方法将多发伤合并休克患者116例依据随机数字表法分为对照组与观察组,每组58例。对照组行积极性液体复苏,观察组行限制性液体复苏。比较两组血清乳酸、凝血功能、炎性指标及抢救效果。结果复苏3 h后,观察组血清乳酸、血清白细胞介素-6、肿瘤坏死因子-α水平均较对照组低,凝血酶原、活化部分凝血活酶时间均较对照组短,且抢救效果优于对照组,差异具有统计学意义(P<0.05)。结论急诊多发伤合并休克患者应用限制性液体复苏可降低血乳酸水平,改善凝血功能并缓解机体炎症反应,有效提升患者抢救效果,降低不良事件的发生率。

Objective To observe the application effect of limited fluid resuscitation in emergency patients with multiple trauma and shock.Methods 116 emergency patients with multiple trauma and shock were randomly divided into the control group and the observation group,58 cases in each group.Control group was given positive fluid resuscitation,while the observation group was given limited fluid resuscitation.The serum lactic acid,coagulation function,inflammatory indexes and rescue effect were compared between the two groups.Results After resuscitation for 3 h,the serum lactic acid,serum interleukin-6 and tumor necrosis factor-αin observation group were lower than those in control group;the prothrombin and activated partial thromboplastin time in observation group were shorter than those in control group;the rescue effect of observation group was better than that of control group.The difference was statistically significant(P<0.05).Conclusion Limited fluid resuscitation in emergency patients with multiple trauma and shock can decrease the level of lactic acid,improve coagulation function,relieve inflammatory response,increase rescue effects and reduce the incidence of adverse events.