基于单中心的冠状动脉病变患者恶性肿瘤患病率调查

Prevalence investigation of malignant tumors in patients with coronary artery diseases based on single clinical center

目的:探讨单中心冠状动脉(冠脉)病变患者恶性肿瘤的发生情况。方法:纳入复旦大学附属中山医院2016年1月至2017年12月申请冠脉造影的20 191例患者,根据病史资料统计冠脉病变及恶性肿瘤患病情况。结果:通过以往冠脉血运重建病史及此次冠脉造影证实存在冠脉病变的患者共18 500例,平均年龄(64.2±9.8)岁。其中,罹患恶性肿瘤的患者共391例(2.1%)。391例恶性肿瘤中,构成比占前5位者分别为泌尿和男性生殖系统恶性肿瘤、肠癌、肺癌、胃食管恶性肿瘤和乳腺癌,分别为18.9%、17.1%、14.1%、13.6%、11.0%。结论:冠脉病变合并恶性肿瘤较为常见,必须加强肿瘤心脏病多学科联合诊疗的临床探索。

Objective:To explore the prevalence of malignant tumors in patients with coronary artery diseases in a single clinical center.Methods:A total of 20 191 patients underwent coronary angiography were selected from January 2016 to December 2017 in Zhongshan Hospital,Fudan University.Coronary artery diseases and the prevalence of concurrent malignant tumors were studied using medical history system.Results:A total of 18 500 patients were definitely diagnosed with coronary artery lesions by their medical history of coronary artery revascularization or angiography.Their mean age was(64.2±9.8)years old.Among these patients,391 had malignant tumors(2.1%).Among the 391 patients,the top five malignant tumors were urological and male reproductive system malignant tumors,colorectal cancer,lung cancer,gastroesophageal malignant tumors and breast cancer,with respective percentages of 18.9%,17.1%,14.1%,13.6%,and 11.0%.Conclusions:Coronary artery diseases complicated with malignant tumors are not unusual in clinical practice.It is urgent to strengthen the clinical cooperation of multidisciplinary diagnosis and treatment on cardio-oncology.