彩色多普勒超声在输卵管积水不孕患者辅助生殖中的应用研究

Application of color Doppler ultrasound to assisted reproductive technology for infertile patients with hydrosalpinx

目的分析卵巢血流动力学参数与卵泡输出率(FORT)的关系,探讨彩色多普勒超声在输卵管积水患者体外受精-胚胎移植(IVF-ET)辅助生殖中的应用价值。方法选取首次接受IVF-ET助孕的239例妇女,其中121例单侧或双侧输卵管积水患者纳入积水组,118例因男方因素不孕者纳入对照组。比较两组卵巢基质动脉血流参数、FORT,并对积水组FORT的相关因素进行分析。结果积水组卵巢基质血流搏动指数(PI)、阻力指数(RI)与对照组比较,差异无统计学意义(P>0.05)。积水组收缩期峰值流速(PSV)、FORT均低于对照组(均P<0.05)。积水组年龄与FORT呈负相关,PSV与FORT呈正相关(均P<0.05)。结论经阴道彩色多普勒超声是评估输卵管积水患者卵巢血供情况的重要手段,结合对患者FORT的评估,可有效预测卵巢反应性。

Objective To analyze the relationship between ovarian hemodynamic parameters and follicular output rate (FORT), and to explore the value of color Doppler ultrasound applied to assisted reproductive technology of in vitro fertilization-embryo transplantation (IVF-ET) in patients with hydrosalpinx. Methods A total of 239 women receiving first IVF-ET as assisted reproductive technology were selected, including 121 cases of unilateral or bilateral hydrosalpinx as hydrosalpinx group, and 118 cases of infertility due to male factors as control group. Ovarian stromal blood flow parameters and FORT were compared between the two groups, and the related factors of FORT in the hydrosalpinx group were analyzed. Results There was no statistically significant difference between the hydrosalpinx group and the control group in ovarian stromal blood flow pulsation index (PI) or resistance index (RI)( P >0.05). The peak systolic velocity (PSV) and FORT in the hydrosalpinx group were lower than those in the control group (all P <0.05). In the hydrosalpinx group, age negatively correlated with FORT, and PSV positively correlated with FORT(all P <0.05). Conclusion Transvaginal color Doppler ultrasound is an important method for evaluating ovarian blood supply in patients with hydrosalpinx, and might achieve effective prediction of ovarian responsiveness in combination with FORT evaluation .