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细胞焦亡在糖尿病肾病中的作用机制研究 被引量：5

A review on mechanism of impact of pyroptosis on diabetic nephropathy
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摘要 糖尿病肾病是免疫炎性疾病,其发病机制包括炎性损伤、糖脂代谢紊乱以及遗传信息等。细胞焦亡是新型的细胞程序性死亡,其经典通路核苷酸结合寡聚化结构域样受体蛋白3、半胱酸-天冬氨酸蛋白酶1、白细胞介素-1β的激活可影响糖尿病肾病的发生与发展。探讨细胞焦亡在糖尿病肾病的作用机制可能是治疗该疾病的新方法。本文就细胞焦亡与糖尿病肾病的关系及中西医结合治疗细胞焦亡等方面的研究进展进行综述。
作者 毛正奇 黄国东
机构地区 广西中医药大学瑞康临床医学院 广西国际壮医医院
出处 《广西医学》 CAS 2019年第8期1020-1022,共3页 Guangxi Medical Journal
关键词 糖尿病肾病 细胞焦亡 炎症因子 综述
分类号 R587.24 [医药卫生—内分泌]
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参考文献6

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  • 2Kazuo Eguchi,Joji Ishikawa,Satoshi Hoshide. Night time blood pressure variability a strong predictor for cardiovascular events in patients with type 2 diabetes[J].American Journal of Hypertension,2009.46-51.
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  • 4A Levin,GL Bakris,M Molitch. Prevalence of abnormal serum vitamin D,PTH,calcium,and phosphorus in patients with chronic kidney disease:Results of the study to evaluate early kidney disease[J].Kidney International,2007.31-38.
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广西医学
2019年 第8期

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