无托槽隐形矫治器治疗成人牙周病

Bracketless invisible orthodontic appliance for treating adult periodontal disease

背景:目前国内外研究中已有学者指出,无托槽隐形矫治器在成人牙周病治疗中能得到更好的应用。目的:观察无托槽隐形矫治器相比于传统疗法治疗成人牙周病的效果。方法:纳入2013年1月至2016年8月于南京医科大学附属口腔医院就诊的120例牙周病患者,采用随机数字表法分为2组:观察组(n=60)接受无托槽隐形矫治技术治疗,对照组(n=60)接受传统固定矫治技术治疗。治疗前及治疗完成后,判定两组牙周健康状况(牙龈指数、牙周探诊深度、龈沟出血指数及菌斑指数),并进行疗效判定,同时检测龈沟液中C-反应蛋白、肿瘤坏死因子α、白细胞介素2及白细胞介素6水平。试验方案已通过南京医科大学附属口腔医院伦理委员会批准,伦理审批号201302036。结果与结论:①治疗完成后,观察组的菌斑指数明显低于对照组(P<0.05),两组牙龈指数、牙周探诊深度、龈沟出血指数比较差异无显著性意义(P>0.05);②观察组的治疗有效率高于对照组(93.3%,80.0%,P<0.05);③治疗完成后,观察组龈沟液中C-反应蛋白、肿瘤坏死因子α及白细胞介素6水平均低于对照组(P<0.05),白细胞介素2水平高于对照组(P<0.05);④结果表明,无托槽隐形矫治器治疗成人牙周病疗效确切,可有效降低相关炎症因子水平。

BACKGROUND:Bracketless invisible orthodontic appliance has been shown to be available for adult periodontal disease.OBJECTIVE:To compare the treatment efficacy between bracketless invisible orthodontic appliance andtraditional method in adult periodontal disease.METHODS:One hundred and twenty cases of periodontal disease admitted at Affiliated Stomatological Hospital of Nanjing Medical University from January 2013 to August 2016 were enrolled,and randomized into observation group(n=60,bracketless invisible orthodontic appliance)and control group(n=60,traditional method).The gingival index,probing depth,sulcus bleeding index and plaque index before and after therapy were detected and the curative effect was assessed.The levels of C-reactive protein,tumor necrosis factor-α,interleukin-2 and interleukin-6 in the gingival crevicular fluid were measured.The study was approved by the Ethics Committee of Affiliated Stomatological Hospital of Nanjing Medical University,approval No.201302036.RESULTS AND CONCLUSION:(1)The plaque index after therapy in the observation group was significantly lower than that in the control group(P<0.05).The gingival index,probing depth,and sulcus bleeding index showed no significant difference between two groups(P>0.05).(2)The total effective rate in the observation group(93.3%)was significantly higher than that in the control group(80.0%)(P<0.05).(3)The levels of C-reactive protein,tumor necrosis factor-α,and interleukin-6 in the gingival crevicular fluid in the observation group were significantly lower than those in the control group(P<0.05),and the level of interleukin-2 was significantly higher than that in the control group(P<0.05).(4)In summary,the efficacy of bracketless invisible orthodontic appliance for treating adult periodontal disease is exact,and can effectively reduce the levels of inflammatory factors.