正念减压对复杂性脊柱转移肿瘤动脉栓塞化疗患者不良情绪与生活质量的影响

Effects of Mindfulness-based Stress Reduction on Adverse Mood and Quality of Life in Patients with Complex Spinal Metastases Undergoing Arterial Chemoembolization

目的探讨正念减压对复杂性脊柱转移肿瘤动脉栓塞化疗患者不良情绪与生活质量的影响。方法选择2014年3月-2018年8月于我院行动脉栓塞化疗的复杂性脊柱转移肿瘤患者120例作为研究对象,按照随机数字表法分为对照组和观察组,各60例。对照组患者给予常规心理健康教育,观察组在对照组的基础上给予正念减压干预,每周1次,共6周。分别采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、疼痛数字量表(NRS-10)及癌症治疗功能评价量表(FACT-G)评估并比较两组患者干预前后焦虑水平、抑郁水平、疼痛程度及生活质量。结果干预前,两组患者SAS、SDS及NRS-10评分比较,差异无统计学意义(P>0.05);干预后,两组评分均明显降低(P<0.05),且观察组显著低于对照组,差异有统计学意义(P<0.05)。干预前,两组患者FACT-G总评分及生理状况、社会/家庭状况、情感状况、功能状况各项评分比较,差异均无统计学意义(P>0.05);干预后,两组患者FACT-G评分均明显升高(P<0.05),且观察组显著高于对照组,差异有统计学意义(P<0.05)。结论应用正念减压对复杂性脊柱转移肿瘤动脉栓塞化疗患者进行干预,可有效减轻其焦虑抑郁情绪,缓解疼痛,提高生活质量,值得临床推广应用。

Objective To explore the effect of mindfulness-based stress reduction on adverse mood and quality of life of patients with complex spinal metastatic tumors undergoing arterial chemoembolization. Methods A total of 120 patients with complex spinal metastatic tumors treated by arterial chemoembolization in our hospital between March 2014 and August 2018 were selected as the study subjects.They were divided into control group and observation group according to random number table method, 60 cases in each group. Patients in the control group were given routine mental health instruction, while patients in the observation group were given mindfulness-based stress reduction intervention on the basis of the control group, once a week, for a total of six weeks. The Self-rating Anxiety Scale(SAS), Self-rating Depression Scale(SDS), Numeric Rating Scale-10(NRS-10) and Functional Assessment of Cancer Therapy-G(FACT-G) were applied to evaluate and compare the anxiety, depression, pain degree and quality of life of patients between the two groups before and after intervention.Results There was no difference in SAS, SDS and NRS-10 scores between the two groups before intervention(P>0.05). After intervention,the scores of the above mentioned decreased significantly in both groups(P<0.05), but they decreased greater in observation group than in control group(P<0.05). As for the FACT-G scores, there were no differences between the two groups before intervention in total scores as well as in physical, social/family, emotional and functional dimension(P>0.05). However, after intervention, the FACT-G scores of the two groups increased significantly in the five dimensions(P<0.05), and the increase of the observation group was more than that of the control group, with significant difference(P<0.05). Conclusion Mindfulness-based stress reduction can effectively relieve anxiety and depression,relieve pain and improve the quality of life in patients with complex spinal metastases undergoing arterial chemoembolization.