血清学指标在评价危重心律失常及其预后中的研究进展

Research Progress of Serological Indicators in the Evaluation of Life-Threatening Arrhythmias and Its Prognosis

心律失常作为心血管系统常见疾病,影响着患者预后,及时有效的指标检测有助于患者病情评估,以帮助临床医师尽早预测识别危重心律失常及具有不良预后转归的患者,指导患者管理。目前,有血清学指标与危重心律失常密切相关,相关指标可预测心房颤动高风险,评估其治疗后复发性,同时与心房颤动患者未来不良心血管事件相关,且在室性心律失常甚至心脏骤停等风险及不良预后的评估中也体现出重要价值。但C反应蛋白、正五聚蛋白3、半乳糖凝集素3和尿酸与心房颤动发生及复发的相关性仍存在争议,未来需进一步研究。

Arrhythmias,as common diseases of the cardiovascular system,affects the prognosis of patients. Timely and effective detection of indicators is helpful for the assessment of the patients′ condition,so as to help clinicians predict and identify patients with critical arrhythmia and adverse prognosis as early as possible,and guide the patient management.At present,there are serological indicators closely related to critical arrhythmias,and relevant indicators predicting the high risk of atrial fibrillation and evaluating its recurrence after treatment,which are also related to future adverse cardiovascular events in the patients,and have important value in evaluating risk and adverse prognosis of ventricular arrhythmias and even cardiac arrest.However,the correlation between C-reactive protein,pentraxin-3,galectin-3 and uric acid and the occurrence and recurrence of atrial fibrillation remains controversial,and further studies are needed in the future.