肥胖在胰腺疾病中的临床研究进展

Clinical Study Progress of Obesity in Pancreatic Diseases

胰腺是人体的重要器官,能够发挥内外分泌功能,在全身代谢、消化、吸收中起中心作用。多种因素可引起胰腺功能或结构变化,导致胰腺疾病的发生。胰腺疾病主要包括急性胰腺炎、慢性胰腺炎、胰腺癌、胰腺囊性肿瘤、脂肪胰等。近年来,随着肥胖人群的逐年增加,其导致的多种病理过程也被进一步阐明。肥胖被认为是一种慢性的低度炎症状态,对多种疾病的发生及发展产生影响。肥胖在胰腺疾病中发挥重要作用,但对于肥胖影响胰腺疾病的发生发展及具体的作用机制仍需要进一步探索。

Pancreas with endocrine and exdocrine function is an important organ,which plays a central role in metabolism,digestion and absorption.Many factors can change its function or structure,leading to the occurrence of pancreatic diseases .Pancreatic diseases mainly include acute pancreatitis,chronic pancreatitis,pancreatic cancer,pancreatic cystic tumors,fatty pancreas and so on.In recent years,with the increasing incidence of obesity year by year,many pathological processes caused by obesity have been further clarified.Obesity is considered to be a chronic,low-grade inflammatory state,which has an impact on the occurrence and development of many diseases.Obesity plays an important role in pancreatic diseases,but the specific mechanisms still need to be further explored.