膜表面荷负电修饰与抗蛋白质污染性能分析

Negatively Charged Surface Modification of Membrane and Its Resistance to Protein Pollution

采用多巴胺和聚苯乙烯磺酸钠作为修饰剂,通过一步反应在微孔聚丙烯膜(MPPM)表面构建了荷负电修饰层。分析了修饰前后膜表面化学组成的变化,考察了修饰膜的亲水性及抗蛋白质污染性能。结果表明,制得的修饰膜具有超亲水性,水通量大(在0.05MPa时,涂覆率为350μg·cm^(-2)的修饰膜水通量可高达3 581 L·m^(-2)·h^(-1)),且对带负电的蛋白质具有很强的抗吸附能力,吸附量几乎为0,蛋白质溶液通量下降率小,残留在膜表面的少量蛋白质可简单地用水清洗除去,展现出很好的应用前景。

Using dopamine and sodium polystyrene sulfonate as modifiers,a negatively charged modification layer was constructed on the surface of microporous polypropylene membrane (MPPM) by one-step reaction. The changes of chemical composition of the membrane surface before and after modification were analyzed. The hydrophilicity and anti-protein fouling performance of the modified membranes was investigated. The results show that the modified membranes have superhydrophilicity and high water flux (at 0.05 MPa operating condition. The water flux of the modified membrane with a coating rate of 350 μg·cm^-2 can reach 3 581 L ·m^-2 ·h^-1). In addition,the modified membranes have strong anti-adsorption capacity for negatively charged proteins. The adsorption amounts are almost zero,the rates of decreased in flux of the protein solution are small,and the small amount of protein remaining on the membrane surface can be simply removed by water cleaning,which this modification membrane shows a good application prospect.