青少年口腔疣状黄瘤病例报道及文献复习

Oral verrucous xanthoma in adolescents: a case report and literature review

目的探讨青少年疣状黄瘤(verruciform xanthoma,VX)的病因、临床表现、诊断及治疗方法,为临床诊疗提供参考。方法对收治的1例青少年腭部肿物病例的临床资料进行分析,并回顾相关文献。结果该例患者腭部肿物经组织病理学检查证实为疣状黄瘤,手术切除,预后良好。文献回顾分析显示,疣状黄瘤是一种罕见的病因不明的良性黏膜皮肤病变,发生率约0.025%～0.094%,好发于中年人群,无明显性别差异。临床表现与鳞状乳头状瘤、寻常疣、纤维瘤、疣状癌和鳞状细胞癌等多种疾病相似,不易鉴别,需要依靠组织病理学诊断。疣状黄瘤局部切除即可治愈,不易复发。结论在临床中遇到青少年的黏膜孤立性肿物,需进行病理检查,避免过度治疗。

Objective To explore the etiology, clinical manifestations, diagnosis and treatment of verruciform xanthoma(VX) in adolescents to provide a reference for clinical diagnosis and treatment. Methods The clinical data of a case of a palatal mass in a juvenile were analyzed, and the related literature was reviewed. Results The palatal mass was proven to be VX by histopathological examination. Surgical resection was performed, and the prognosis was good. A review of the literature shows that VX is a rare benign mucosal skin lesion of an unknown etiology, with an incidence of approximately 0.025%-0.094%;VX is mostly found in middleaged people, with no significant difference by sex. The clinical manifestations are similar to those of a variety of diseases, such as squamous papilloma, verruca vulgaris, fibroma, warty carcinoma and squamous cell carcinoma, which are not easy to distinguish and require histopathological diagnosis. The treatment of choice is surgical excision, with a low recurrence rate. Conclusion In the clinical experience of solitary mucosal masses in juveniles, it is necessary to send biopsy for pathological examination and avoid overtreatment.