术前CT淋巴结定位联合纳米碳示踪技术在胃癌根治术中的应用

Efficacy of CT localization combined with carbon nanotechnology on identification of lymph node in radical gastrectomy of gastric cancer

目的探讨术前CT淋巴结定位联合纳米碳示综技术在胃癌根治术中的应用效果。方法选取2016年1月—2017年8月江西省肿瘤医院腹部外科收治的64例拟行胃癌根治术患者作为研究对象,随机分为对照组和联合组;两组患者术前均进行螺旋平扫加增强CT检查,对淋巴结进行术前定位,联合组在此基础上使用纳米碳示踪技术。统计检出淋巴结数目、转移情况及复发率,分析其在胃癌根治术中的指导效果。结果对照组共检出淋巴结737枚,平均每例切除(23.28±8.24)枚,联合组共检出淋巴结963枚,平均每例切除(30.56±7.17)枚,联合组淋巴结检出数与第2站平均检出数高于对照组(P<0.05)。联合组淋巴结转移阳性率为23.47%,高于对照组淋巴结转移率(19.02%)(P <0.05);随访记录显示联合组复发率约为9.37%,低于对照组12.50%的复发率(P<0.05)。结论术前CT定位联合纳米碳示踪技术对胃癌根治术淋巴结清扫具有很好的临床指导意义。

Objective To investigate the efficacy of lymph node localization by preoperative CT combined with carbon nanoscale technique in radical gastrectomy for gastric cancer. Methods Totally 64 cases of gastric carcinoma who were admitted into our hospital from January 2016 to August 2017 for radical surgery were randomly divided into control group and combination group. All patients were performed with spiral plain and enhanced CT examination for preoperative localization lymph node. Patients in the combination group received additional carbon Nano-tracer technology. Results A total of 737 lymph nodes were identified in control group, with an average of (23.28 ± 8.24) lymph nodes eradicated. A total of 963 lymph nodes were detected in combination group, with an average of (30.56 ± 7.17) eradicated. The average number of lymph nodes and second stations in the combinationgroup was significantly higher than those in the control group (P < 0.05). Postoperative pathological results showed that the positive rate of lymph node metastasis in the combination group was increased significantly than that in the control group (23.47% vs 19.02%, P < 0.05). Following up results showed that the recurrence rate for 1.5 years of recurrence rate in the combination group was slightly lower than that in the control group (9.37% vs 12.50%). Conclusions Preoperative CT localization combined with carbon Nano tracing technique is of great guiding significance for lymph node dissection in radical gastrectomy.