937例肾癌患者的临床病理特征分析

Analysis of Clinicopathological Characteristics of 937 Patients with Renal Cell Carcinoma

目的总结肾癌的临床病理特征和诊疗情况。方法对2016年1月至2018年6月在郑州大学第一附属医院住院接受手术切除治疗的肾癌患者进行筛选,共得到资料较为完整的937例。现对937例患者的发病情况、临床病理特征进行分析总结。结果 937例肾癌患者中,男591例(63.1%),女346例(36.9%),男女比例为1.7:1.0。患者年龄12~86岁,中位年龄54岁。40~69岁为肾癌的高发年龄(78.8%)。有肾癌相关临床症状者372例(39.7%),无症状肾癌患者535例(57.1%),非肾癌症状者30例(3.2%)。左肾肾癌435例(46.4%),右肾肾癌498例(53.1%),双肾肾癌4例(0.4%)。肾癌肿瘤直径0.5~19 cm,中位数4.6 cm。病理结果:透明细胞癌818例(87.3%),嫌色细胞癌58例(6.2%),乳头状细胞癌30例(3.2%),其他31例(3.3%)。结论女性肾癌患者比例相对较高,肾癌发病于上极和下极较多,透明细胞癌和嫌色细胞癌占的比例高于一般水平,乳头状癌的比例低于一般水平。

Objective To analysis the clinicopathological characteristics, diagnosis and treatment of renal cell carcinoma.Methods The patients were screened who underwent surgical resection treatment with renal cell carcinomain the First Affiliated Hospital of Zhengzhou University,from January 2016 to June 2018. Above all, 937 patients werecollected. The patients’ clinicopathological characteristics, diagnosis and treatment were analyzed and summarized.Results Among the 937 cases, 591(63.1%) were male and 346(36.9%) were female. The ratio of male to female was 1.7:1.0. The age of the disease was between 12 and 86 years old, with an median age of 54. The patients with age from 40 to 69 had the highest rate of renal cell carcinoma(78.8%). There were 372 patients(39.7%) with related clinical symptoms of renal cell carcinoma, 535 patients(57.1%) with asymptomatic renal cell carcinoma, and 30 patients(3.2%) with non-related symptoms. There were 435 patients(46.4%) on the left side, 498 patients(53.1%) on the right and 4 patients on both the two sides. The size ranged from 0.5 to 19 cm in diameter, with an median diameter of 4.6 cm. Pathological results: 818 patients(87.3%) were clear cell renal cell carcinoma, 58 patients(6.2%) were chromophobe renal cell carcinoma, 30 patients(3.2%) were papillary renal cell carcinoma, and 31 patients were other patients(3.3%).Conclusion The proportion of women with renal cell carcinoma is relatively higher than men with renal cell carcinoma, renal cell carcinoma is more likely located in the upper and lower side, the proportion of clear cell and chromophobe cell renal cell carcinoma are higher,the proportion of papillary renal cell carcinomais lower.