摘要
肠道菌群被称为人体的"第二基因组",参与了代谢、消化、炎症及免疫等多项生理功能的调节。新的研究显示肠道菌群可通过神经、内分泌以及免疫途径参与肠道及中枢神经系统的双向调节。肠道菌群与脑卒中的关系密切,已成为国内外研究的热点。肠道菌群不仅与脑卒中的危险因素如高血压、糖尿病、肥胖及动脉粥样硬化等密切相关,还影响着脑卒中的发生及预后。研究肠道菌群与脑卒中的相关性,可为脑卒中的预防及治疗提供新的途径。
Intestinal flora,known as the second human genome,is involved in the regulation of multiple physiological functions such as metabolism,digestion,inflammation and immunity.New studies have revealed that intestinal flora plays an important role in bidirectional communications between the gut and central nervous system by means of neural,endocrine and immunological pathways.Intestinal flora is closely linked with stroke,which has become a research focus in the world.Intestinal flora is not only closely related to risk factors of stroke such as hypertension,diabetes,obesity and atherosclerosis,but also affects the occurrence and prognosis of stroke.To study the correlation between intestinal flora and stroke will provide a new approach for the prevention and treatment of stroke.
作者
孙亚鲁
尹勇
王晓梅
SUN Yalu;YIN Yong;WANG Xiaomei(Kunming Medical University,Kunming 650500,China;Department of Rehabilitation Medicine,the Second People′s Hospital of Yunnan Province,Kunming 650021,China)
出处
《医学综述》
2019年第9期1782-1786,共5页
Medical Recapitulate