三仁汤联合法莫替丁治疗小儿急性胃炎42例临床观察

Treatment of 42 Cases of Acute Gastritis with Accumulated Gastric Heat Syndrome by Sanren Decoction and Famotidine

目的:观察三仁汤联合法莫替丁治疗胃有积热证急性胃炎的临床疗效。方法:选取胃有积热证急性胃炎患儿84例,随机分为对照组与观察组各42例,对照组予法莫替丁治疗,观察组在法莫替丁治疗的同时加用三仁汤,比较两组的临床疗效、中医证候积分和不良反应发生率。结果:观察组临床疗效优于对照组,其中医证候积分和不良反应发生率均低于对照组,差异有统计学意义(P<0.05)。结论:对胃有积热证急性胃炎患儿采用三仁汤联合法莫替丁治疗能够提高临床效果,有利于降低其中医证候积分,缓解临床症状,且安全性较好,值得临床上推广应用。

Objective To explore the clinical effect of Sanren Decoction combined with famotidine in the treatment of acute gastritis with accumulation of heat in stomach. Methods 84 cases of acute gastritis with accumulated heat in stomach were selected as control group, 42 cases were treated with famotidine, and 42 cases were treated with Sanren Decoction at the same time with famotidine. As observation group, the clinical efficacy, TCM syndrome score and incidence of adverse reactions were compared between the two groups. Results The clinical efficacy of the observation group was better than that of the control group, and the scores of TCM syndromes and the incidence of adverse reactions were lower than those of the control group, with statistical significance(P<0.05). Conclusion Sanren Decoction combined with famotidine can improve the clinical effect of children with acute gastritis with accumulated heat in stomach, reduce the integral of TCM syndromes, relieve clinical symptoms, and have good safety. It is worth popularizing and using in clinic.