国产3D打印机打印复杂先天性心脏病心脏模型的精确性评估

Accuracy evaluation of cardiac models of cases with complex congenital heart disease printed by domestic 3D printers

目的评估基于心脏CT数据的3D建模,以及应用国产3D打印机进行打印的复杂先天性心脏病(先心病)患者心脏模型的精确性。方法 2018年4月至2018年6月,我院应用国产3D打印机对50例复杂先心病患者的心脏进行3D打印。患者中位年龄24个月(1个月~61岁),病种包括肺动脉闭锁、右心室双出口和大动脉转位等。每例患者选择3个测量位点(共150个),行Pearson相关系数计算、配对t检验及Bland-Altman分析。结果 Pearson相关系数是0.997。对CT-模型测量值的差值进行正态性检验。D检验中,P=0.2,且Q-Q图显示数据点与理论直线重合度较高;差值平均(-0.07±0.67)mm,P=0.196。Bland-Altman分析中,差值的一致性界值区间(-1.29 mm,1.16 mm),有143/150(95.33%)点在一致性界值区间内。结论基于心脏CT数据的3D建模,应用国产的3D打印机进行打印的复杂先心病心脏模型具有良好的精确性。

To evaluate the accuracy of 3D models of patients with complex congenital heart disease(CHD) printed by domestic 3D printers based on cardiac CT data. Methods From April 2018 to June 2018, our hospital used domestic 3D printers to print the hearts of 50 patients with complex CHD. The median age of the patients was 24 months(1 month to 61 years), and the diseases included pulmonary atresia, right ventricular double outlet and transposition of aorta. 3 measurement sites(150 in total) were selected for each patient. Pearson correlation coefficient calculation, paired t test and Bland-Altman analysis were performed. Results Pearson correlation coefficient is 0.997.The difference of the measured value of CT-model was tested for normality. P was 0.2 of the D test. The Q-Q graph showed that the data point and the theoretical line were highly overlapped. The mean difference was(-0.07±0.67)mm, P=0.196. In Bland-Altman analysis, the consistency boundary value interval of the difference was(-1.29 mm, 1.16 mm) between which there were 143/150(95.33%) points. Conclusion 3D models of patients with complex CHD printed by domestic 3D printers based on cardiac CT data have good accuracy.