光动力疗法治疗阴囊淋巴管瘤一例

Photodynamic therapy for scrotal lymphangioma:a case report

患者男,23岁,5年前出现阴囊小水疱,逐渐布满整个阴囊,摩擦易破溃。体检:阴囊弥漫粟米大小水疱,疱液呈乳白色,并可见乳糜状渗液。皮损组织病理:真皮内可见大小不一的淋巴管增生扩张。免疫组化:D2-40、CD31阳性。诊断:阴囊淋巴管瘤。采用氨基酮戊酸光动力疗法治疗,治疗后水疱减少,无明显渗液,随访1年无瘢痕等并发症,无明显复发。

A 23-year-old male patient developed vesicles on the scrotum 5 years prior to this presentation.Then,vesicles gradually affected the whole scrotum,whick easily ruptured due to friction.Physical examination showed diffuse millet-sized vesicles on the scrotum with milky white fluids,and exudates with chyle-like appearance.Histopathological examination revealed proliferating and dilated lymphatic vessels with different sizes of lumens in the dermis.Immunohistochemical study showed positive staining for D2-40 and CD31.The patient was diagnosed with scrotal lymphangioma,and received photodynamic therapy with aminolevulinic acid.After the treatment,the number of vesicles markedly decreased,and no obvious exudates were observed.During 1 year of follow up,no scars or other complications occurred,and no obvious relapse was found.