单纯鼾症与阻塞性睡眠呼吸暂停低通气综合征患者睡眠期间的有效通气量、血氧浓度及睡眠和生活质量的比较

Comparison of Effective Ventilation Volume,Blood Oxygen Concentration and Sleep and Quality of Life in Patients with Simple Snoring and Obstructive Sleep Apnea Hypopnea Syndrome during Sleep

【目的】探讨单纯鼾症与阻塞性睡眠呼吸暂停低通气综合征(SAHS)患者睡眠期间的有效通气量指标睡眠呼吸暂停低通气指数(AHI)、动脉血氧饱和度(SaO2)及睡眠和生活质量。【方法】随机选取2017年1月至2018年5月本院诊治的50例阻塞性SAHS患者(A组)、50例单纯鼾症患者(B组)和50例健康体检者(C组)。比较三组睡眠期间AHI、SaO2和睡眠质量等,并采用Calgary生活质量量表评估A组和B组患者生活质量并比较。【结果】A组、B组、C组AHI依次升高,SaO2依次降低,且组间比较差异有统计学意义(P<0.05);A组和R组以浅睡眠为主,C组以深睡眠为主,且A组浅睡眠比例显著高于B组;A组日常活动、社会交往、情感及症状各方面评分均显著低于B组.其差异均有统计学意义(P<0.05)。【结论】阻塞性SAHS患者的AHI升高,SaO2降低,以浅睡眠为主,且生活质量下降。

【Objective】To investigate the effective ventilation volume,blood oxygen concentration,sleep and quality of life in patients with simple snoring and obstructive sleep apnea hypopnea syndrome(OSAS)during sleep.【Methods】From January 2017 to May 2018,50 patients with obstructive SAHS(group A),50 patients with simple snoring(group B)and 50 healthy people(group C)were randomly selected.AHI,SaO2 and sleep quality during sleep were compared among the three groups.The quality of life of the group A and the group B was assessed by Calgary Quality of Life Scale and compared.【Results】The AHI of the group A,the group B and the group C increased in turn,and the SaO2 ecreased in turn,with significant difference between groups(P<0.05).Shallow sleep was dominant in the group A and the group B,while deep sleep was dominant in the group C,and the proportion of shallow sleep in the group A was significantly higher than that in the group B.The scores of daily activities,social interaction,emotions and symptoms in the group A were significantly lower than those in the group B,with significant difference(P〈0.05).【Conclusion】The patients with obstructive SAHS had higher AHI and lower SaO2,mainly with shallow sleep and lower quality of life.