帕金森病伴轻度认知功能障碍的研究进展

Mild cognitive impairment in Parkinson disease

帕金森病伴发的轻度认知功能障碍,对患者的基本生活功能影响较小,但往往会演变成帕金森痴呆,从而显著影响患者的生存质量及预后。因此,了解这一疾病,并对其进行早期干预具有十分重要的意义。现从帕金森病轻度认知功能障碍的定义、临床表型、诊断标准、鉴别诊断、发病机制、危险因素及治疗等方面进行综述,为相关研究提供参考。

Although mild cognitive impairment associated with Parkinson disease does little effect on the basic living functions of patients, it often leads to Parkinson disease dementia, which significantly affects the quality of life and prognosis of patients. Therefore, it is of great significance to understand this disease and make early intervention. This article reviews the definition, clinical phenotype, diagnostic criteria, differential diagnosis, pathogenesis, risk factors and the treatment of mild cognitive impairment in Parkinson's disease, so as to provide references for relevant studies.