甲状腺功能亢进症合并甲状腺癌临床诊疗分析

Diagnosis and treatment of clinical analysis of hyperthyroidism patients coexisted thyroid carcinoma

目的探讨甲状腺功能亢进症(简称"甲亢")合并甲状腺癌的临床诊断与治疗方法。方法回顾性分析许昌市建安区人民医院普外科2008年11月至2017年12月手术治疗的15例甲亢合并甲状腺癌患者的临床资料,对其诊断与治疗进行讨论。结果本组甲亢合并甲状腺癌的发生率为8.19%(15/183);乳头状癌12例,滤泡型癌1例,髓样癌1例,滤泡型乳头状癌1例,其中微小乳头状癌占66.67%(10/15);15例均获得随访,平均随访时间为13.25月,无复发及死亡病例发生。结论甲亢合并甲状腺癌无特征性临床表现及特异性诊断指标,通过加强认识,提高警惕,综合分析,手术治疗,预后较好。

Objective To explore the clinical diagnosis and treatment of hyperthyroidism patients coexisted thyroid carcinoma. Methods A retrospective analysis was made in 15 cases with hyperthyroidism patients coexisted thyroid carcinoma who were operated from Nov. 2008 to Dec. 2017 in Department of General Surgery of Jian’an District Peoples’ Hospital. Results The incidence of hyperthyroidism patients coexisted thyroid carcinoma was 8.19%(15/183) in our study. All 15 patients included 12 papillary thyroid carcinoma, 1 follicular thyroid carcinoma, 1 medullary thyroid carcinoma, and 1 follicular papillary carcinoma. Among them, papillary thyroid microcarcinoma accounted for 66.67%(10/15). All 15 postoperative patients were followed up and the mean time was 13.25 months. Neither recurrence nor mortality occurred during the period. Conclusions Hyperthyroidism patients coexisted thyroid carcinoma have no characteristic clinical manifestations or specific diagnosis indicators. The prognosis can be good through strengthening awareness, improving vigilance, comprehensive analysis and surgical treatment.