龙胆祛湿汤加减联合海棠丁香凝胶治疗亚急性湿疹36例

Clinical effect of modified Longdan Qushi decoction combined with Haitang Dingxiang gel in treatment of subacute eczema: An analysis of 36 cases

目的:观察龙胆祛湿汤加减联合海棠丁香凝胶治疗亚急性湿疹(湿热蕴肤型)的临床疗效。方法:将76例亚急性湿疹(湿热蕴肤型)患者随机分为治疗组36例与对照组40例。治疗组采用龙胆祛湿汤加减联合海棠丁香凝胶治疗,对照组采用盐酸左西替利嗪治疗。观察2组治疗前后症状体征评分,评定临床疗效。结果:总有效率治疗组为97. 22%,对照组为82. 50%,组间比较,差异有统计学意义(P <0. 05)。结论:龙胆祛湿汤加减联合海棠丁香凝胶治疗亚急性湿疹(湿热蕴肤型)的临床疗效优于盐酸左西替利嗪治疗,值得临床推广应用。

Objective: To investigate the clinical effect of modified Longdan Qushi decoction combined with Haitang Dingxiang gel in the treatment of subacute eczema with the syndrome of damp-heat accumulation in the skin. Methods: A total of 76 patients with subacute eczema with the syndrome of damp-heat accumulation in the skin were enrolled and randomly divided into treatment group with 36 patients and control group with 40 patients. The patients in the treatment group were given modified Longdan Qushi decoction combined with Haitang Dingxiang gel,and those in the control group were given levocetirizine hydrochloride. The scores of signs and symptoms were observed before and after treatment to assess clinical response. Results: There was a significant difference in overall response rate between the treatment group and the control group( 97. 22% vs 82. 50%,P < 0. 05). Conclusion: Modified Longdan Qushi decoction combined with Haitang Dingxiang gel has a better clinical effect than levocetirizine hydrochloride in the treatment of subacute eczema with the syndrome of damp-heat accumulation in the skin and thus holds promise for clinical application.