质量控制图在标准物质稳定性评估中的应用

Application of Control Chart for Assessment of Stability of Reference Materials

标准物质稳定性评估是标准物质研制的一个重要环节,目的是评估标准物质量值在一定时间内的波动情况,并据此给出标准物质有效期。常用的方法是线性回归趋势分析和方差分析法。根据质量控制图的特点及标准物质稳定性评估的实际需要,探索将质量控制图应用于标准物质量值的稳定性监测与评估工作中。通过对比发现,质量控制图具有灵敏直观的特点,可以作为标准物质稳定性评估的一个有效手段。

The assessment of stability of reference materials is an important stage of the development.The aim of assessment of stability is to demonstrate the changes of the values, and give the period of validity for reference materials.The common methods are trend analysis by least squares regression and variance analysis.According to the characteristics of control charts and the practical needs of stability evaluation of reference materials, the application of control charts to stability monitoring and evaluation of reference materials is explored.By the comparison, it can be found that control chart is very sensitive and intuitive.Control chart can be a useful method for the assessment of stability.