拟孢囊菌属放线菌的研究进展

Recent advances on the genus Kibdelosporangium

拟孢囊菌属(Kibdelosporangium)是一个经典的丝状放线菌类群。自Shearer等于1986年建立该属以来,不断有新的菌株从不同生境中被纯培养分离得到,目前已有效发表8个种、2个亚种。拟孢囊菌属作为稀有放线菌属,是获得新型抗生素类次生代谢产物的重要资源。本文结合我们分离到的一株该属菌株的功能研究、基因组分析和相关文献资料,系统综述了拟孢囊菌属放线菌的建立、分类学特征、属内种的分布、活性次级代谢产物的发现以及其他功能应用和开发前景,以期为该属其他新分离菌株的分类鉴定、新颖次级代谢产物的发现、功能基因资源的挖掘与开发提供借鉴。

The genus Kibdelosporangium is a classical group of actinomycetes. Since the establishment of this genus in 1986 by Shearer et al., new strains have been isolated from different habitats by pure culture methods, and8 species and 2 subspecies have been published. Kibdelosporangium is a rare actinomycete genus and an important resource for obtaining new secondary metabolites. Based on the function and genome analysis of a newly isolated strain and the related literature of the genus Kibdelosporangium, we systematically summarize the research advances of the genus Kibdelosporangium, including the genus establishment, taxonomic characteristics,distribution of the species, the discovery of active secondary metabolites and other functional applications and development prospects. This review provides references for the classification and identification of other new isolates, the discovery of novel secondary metabolites, and the exploitation of functional gene resources from the genus Kibdelosporangium in the future.