童年创伤对健康青年认知功能的影响

Impact of childhood trauma on cognitive function in the healthy young adults

目的评估童年创伤对健康青年成人认知功能的影响。方法2012年2月以来3次利用童年创伤问卷筛查出有童年创伤以及不伴任何形式童年创伤的健康青年,分别完成威斯康星卡片分类测验(WCST)、Stroop测验及韦氏记忆量表(WMS)连线测验、词语流畅测验等评估。结果伴童年创伤组(n=90)在词语流畅性测验、WMS视觉再生分测验以及WCST中正确应答数、错误应答数、持续错误数及完成分类数与无童年创伤组(n=104)相比差异有统计学意义,童年创伤总分与视觉再生结果呈负相关,与连线测验B、WCST错误应答数呈正相关,不同童年创伤类型的数量与Stroop测验、WCST正确应答数、WMS部分结果呈负相关(均P<0.05)。结论伴童年创伤的健康青年的认知功能受损,童年创伤越严重或不同创伤数量越多,认知功能越差。

Objectives To assess the impact of childhood trauma on cognitive function in healthy young adults.Methods Three times since February 2012,the Childhood Trauma Questionnaire(CTQ) was used to screen out healthy young people with childhood trauma and without any form of childhood trauma.These participants were then evaluated using the Wisconsin Card Sorting Test(WCST),the Stroop Test,Trail Making Test,Verbal Fluency Test,and the Wechs Memory Scale(WMS).Results The performance of young adults with childhood trauma(n=90) was significantly different in the Verbal Fluency Test,the visual regenerative test of WMS and WCST compared with those with no childhood trauma(n=104).The total score of CTQ was negatively correlated with results of Visual Reproduction and Trail Making Test B,while it was positively correlated with results of WCST ervor response;the number of different types of childhood trauma was negatively correlated with the Stroop test,number of WCST correct response and partial results and partial results of WMS(all P<0.05).Conclusions The cognitive function of healthy young people with childhood trauma is impaired.The more severe the trauma in childhood or the higher the number of different traumas,the worse is their cognitive function.