妇科良性疾病盆腔积液液量及其CA125相关因素分析

Analysis of pelvic effusion volume and related factors of CA125 in gynecological benign diseases

目的分析妇科良性疾病盆腔积液量及其CA125相关因素。方法选取医院妇科良性疾病患者300例作为患病组,另随机选取同期医院门诊体检合格健康妇女300例作为未患病组,统计2组盆腔积液量、血清和腹腔液CA125含量,线性回归分析盆腔积液量及其CA125相关因素。结果患病组子宫内膜异位症者盆腔积液量多于未患病组(P <0. 05)。线性回归分析结果显示,盆腔积液量相关因素包括年龄、体质量指数、子宫内膜异位症(P <0. 05)。患病组子宫肌瘤、卵巢囊肿、子宫内膜异位症患者血清、腹腔液CA125含量均高于未患病组(P <0. 05),子宫内膜异位症患者血清、腹腔液CA125含量均高于子宫肌瘤、卵巢囊肿患者(P <0. 05),子宫肌瘤患者血清、腹腔液CA125含量均高于卵巢囊肿患者(P <0. 05)。结论妇科良性疾病盆腔积液量及其CA125相关因素包括年龄、体质量指数、子宫内膜异位症。

Objective To analyze the amount of pelvic effusion in gynecological benign diseases and the related factors of CA125. M ethods 300 patients with benign gynecological diseases were selected as the disease group, and 300 eligible healthy women in the same period were randomly selected as the non-disease group. The amount of pelvic effusion and CA125 in serum and peritoneal fluid of the two groups were counted. Linear regression analysis was used to analyze the amount of pelvic effusion and the related factors of CA125. Results The amount of pelvic effusion in patients with endometriosis was more than that in patients without endometriosis ( P < 0 .0 5 ). Linear regression analysis showed that the related factors of pelvic effusion volume included age, body mass index and endometriosis ( P < 0 .0 5 ). The levels of CA125 in serum and peritoneal fluid of patients with uterine leiomyoma, ovarian cyst and endometriosis in the diseased group were higher than those in the non-diseased group ( P < 0. 0 5 ). The levels of CA125 in serum and peritoneal fluid of patients with endometriosis were higher than those of patients with uterine leiomyoma and ovarian cyst ( P < 0 .0 5 ). The levels of CA125 in serum and peritoneal fluid of patients with uterine leiomyoma were higher than those of patients with ovarian cyst ( P < 0 . 0 5 ). Conclusion The amount of pelvic effusion in gynecological benign diseases and its CA125 related factors include age, body mass index and endometriosis.