帕金森病患者情绪与情绪词注意偏向相关分析

Investigation of correlations between the emotions and attentional bias to emotional words in patients with Parkinson's Disease

目的探讨慢性帕金森病(Parkinson's Disease,PD)患者情绪与注意偏向相关性。方法将80例PD患者及80例健康对照者(health controls,HC)作为研究对象;所有被试的情绪状况水平采用焦虑症状自评量表(Self-Rating Anxiety Scale,SAS)和抑郁症状自评量表(Self-rating depression scale,SDS)进行评估;注意偏向评估采用中文情绪词stroop测试进行评估。结果 PD组在SDS得分方面高于HC组,差异有统计学意义[(50.60±10.30)分vs(44.11±12.14)分,t=-3.645,P<0.001];PD组在负性词的反应时高于HC组,差异有统计学意义[分别为(1698.71±199.86)ms,(1625.95±241.64)ms;t=-2.076,P=0.040];PD患者对负性词反应时与SDS量表得分呈正相关(r=0.241,P=0.031)。结论 PD患者存在情绪和对注意偏向方面的异常,抑郁情况与对负性词的注意偏向密切相关。

Objective To explore the correlations between the emotions and attentional bias to emotional words in patients with Parkinson’s Disease. Methods A total of 80 PD patients were compared with matched 80 health controls(HC). Emotions of all the subjects were assessed by Self-Rating Anxiety Scale(SAS)、Self-Rating Depression Scale(SDS);that assessed the Attentional bias of all the subjects were assessed by Chinese Emotional Stroop Task. Results The score of SDS in PD group were higher than the HC group[(50.60±10.30)score vs(44.11±12.14)score,t=-3.645,P<0.001]. The comparison between PD group and HC group on the reaction time of negative-related words were significant[(1698.71±199.86)ms,(1625.95±241.64)ms respectively;t=-2.076,P=0.040];Response time to negative words were positively correlated with SDS score in PD patients(r=0.241,P=0.031). Conclusion The studies suggest prevalence of emotions and attentional bias problems in PD patients,Depression is closely related to attention to negative-related words.