无创通气对慢性阻塞性肺疾病急性加重期患者治疗依从性及生活质量的影响

Influence of non-invasive ventilation on treatment compliance and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease

目的探讨无创通气对慢性阻塞性肺疾病急性加重期患者治疗依从性及生活质量的影响。方法回顾性分析2016年5月～2018年5月我院接诊的124例慢性阻塞性肺疾病急性加重期患者的临床资料,按照治疗方法的不同将其分为治疗组(n=68)和对照组(n=56)。对照组患者应用常规方法进行治疗,治疗组患者在常规治疗基础上应用无创通气进行治疗。比较分析两组患者治疗后的血气指标[血氧分压(PaO2)、二氧化碳分压(PaCO_2)、血液酸碱度(pH值)、呼吸困难评分]情况、治疗依从性及生活质量评分。结果两组患者治疗前的PaO2、PaCO_2、pH值及呼吸困难评分比较,差异无统计学意义(P>0.05)。治疗组患者治疗后的PaO2、p H值均明显高于对照组,PaCO_2和呼吸困难评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗组患者治疗后的总依从率为98.53%,高于对照组的75.00%,差异有统计学意义(P<0.05)。治疗组患者治疗后的躯体疼痛、社会功能、心理功能及精神健康评分均明显高于对照组,差异有统计学意义(P<0.05)。结论应用无创通气对慢性阻塞性肺疾病急性加重期患者进行治疗,能够明显改善患者的血气指标和生活质量,提高其治疗依从性,值得在临床大力推广。

Objective To investigate the influence of non-invasive ventilation on treatment compliance and quality of life in patients with acute exacerbation of chronic obstructive pulmonary disease. Methods The clinical data of 124 patients with acute exacerbation of chronic obstructive pulmonary disease admitted to our hospital from May 2016 to May 2018 were retrospectively analyzed. The patients were divided into the treatment group (n=68) and the control group (n=56) according to the different treatment methods. Patients in the control group were treated with the conventional method, while patients in the treatment group were treated with non-invasive ventilation on the basis of conventional treatment. The blood gas index (blood oxygen partial pressure [PaO2], carbon dioxide partial pressure [PaCO2], pH and dyspnea score), treatment compliance and quality of life score were compared between the two groups after treatment. Results There were no significant differences in PaO2, PaCO2, pH and dyspnea score between the two groups before treatment (P>0.05). The PaO2 and pH value in the treatment group were significantly higher than those in the control group, the PaCO2 and dyspnea score in the treatment group were significantly lower than those in the control group, and the differences were statistically significant (P<0.05). The total compliance rate of the treatment group was 98.53%, which was much higher than that of the control group (75.00%), and the difference was statistically significant (P<0.05). The scores of somatic pain, social function, psychological function and mental health in the treatment group were significantly higher than those in the control group, and the differences were statistically significant (P<0.05). Conclusion The application of non-invasive ventilation in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease can significantly improve the blood gas index and quality of life, and improve the treatment compliance, which is worth promoting in clinical practice.