经口内镜下肌切开术对贲门失弛缓症患者围术期心理状态及临床症状的影响

The effect of peroral endoscopic myotomy on perioperative psychological state and clinical symptoms in patients with achalasia

目的探讨经口内镜下肌切开术(POEM)对贲门失弛缓症(AC)患者围术期心理状态及临床症状的影响。方法我院收治57例AC患者,均行POEM治疗,比较手术前后焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、ECKARDT症状评分及36项健康调查简表(SF-36)评分变化。结果所有患者均手术成功。患者术后SAS、SDS评分均较术前明显降低(P<0. 05)。术后6个月,患者ECKARDT评分与术前比较差异有统计学意义,SF-36量表各维度评分均较术前明显增高(P <0. 05)。结论 AC患者行PEOM治疗能够显著改善患者心理状态及临床症状,提高生活质量。

Objective To investigate the effect of peroral endoscopic myotomy( POEM) on perioperative psychological state and clinical symptoms in patients with achalasia( AC).Methods Fifty-seven patients with AC admitted to our hospital were treated by POEM.The changes in scores of self-rating anxiety scale( SAS),self-rating depression scale( SDS),ECKARDT symptoms and 36-item short form( SF-36) were compared before and after surgery.Results All patients’ surgeries were successful. The SAS score and SDS score of patients after surgery were significantly lower than those before surgery( P <0. 05).The ECKARDT score after 6 months of surgery was significantly different when compared with that before surgery( P < 0. 05). The scores of different dimensions in the SF-36 scale after surgery were significantly higher than those before surgery( P <0. 05).Conclusion PEOM for AC can significantly improve the psychological state and relieve the clinical symptoms in patients,and improve their quality of life.