^(125)I放射性粒子植入在口腔颌面部恶性肿瘤治疗中的应用

Application of 125I Radioactive Seed Implantation in Treatment of Oral and Maxillofacial Malignant Tumors

如何提高口腔颌面部恶性肿瘤的治愈率、生存率和保持较高的生存质量,一直是学者们研究的焦点之一。彻底手术切除肿瘤组织,常会导致严重的面部畸形和功能障碍,故目前对其常采用以手术为主配合化疗或放射治疗的综合治疗方式。近年来研究结果表明,应用^(125)I放射性粒子植入的近距离放射治疗对缩小口腔颌面部恶性肿瘤的瘤体和减少复发都有较好的效果。本文对^(125)I粒子在口腔颌面部恶性肿瘤治疗中的的临床应用等方面进行总结,以期为临床提供治疗思路。

How to improve the cure rate and survival rate of oral and maxillofacial malignant tumor,and maintain a higher quality of life,have been one of the focus of the scholars study.Radical resection of oral and maxillofacial malignant tumor often leads to severe facial deformity and dysfunction,such as oral cavity,so now the chemotherapy or radiotherapy combined with surgical treatment is often used.In recent years,studies have shown that close range radiotherapy with 125I radioactive seed implantation is effective in reducing tumor size and reducing recurrence of oral and maxillofacial malignant tumors.In this paper,the clinical application of 125I radioactive seed in the treatment of oral and maxillofacial malignant tumors is described.