单取代芳基氮杂富勒烯的优化合成

Optimization of Synthesizing Monoarylated Aza[60] fullerene

杂富勒烯以其独特的结构和新奇的性质吸引了众多科学家的目光,其中氮杂富勒烯是目前较为广泛研究的一类杂富勒烯,但其较低的合成产率和较差的稳定性阻碍了人们的深入研究。本研究对稳定性较好的一类单取代芳基氮杂富勒烯的合成过程进行了详细研究和优化,通过改变原料投料比例和反应时间使得从羰基内酰胺化合物到单取代芳基氮杂[60]富勒烯的单步产率由42%提高到70%,这对于研究氮杂富勒烯的形成机理,考察氮杂富勒烯的结构及化学物理性质并拓宽其应用范围具有重要意义。

The heterofullerenes have attracted much attention owing to its unique structure and properties.Among them,azafullerenes are the only known heterofullerene that have been widely investigated,but its low synthetic yield and poor stability hinders its extensive research.In this study,the synthesis process of monosubstituted azafullerenes with better stability was studied and optimized in detail.The ratio of starting materials and reaction time have been changed,and the single-step yield has increased efficiently from 42% to 70%.This is important for studying the formation mechanism of azafullerenes,probing the structure and chemical-physical properties of azafullerenes and broadening their application range.