成人烧伤脓毒症患者死亡的危险因素Logistic回归分析

Logistic regression analysis of risk factors for death in adult patients with burned sepsis

目的探讨成人烧伤脓毒症患者死亡的危险因素Logistic回归分析。方法选择2010年7月～2016年7月收治的成人烧伤患者224例作为研究对象,根据患者是否发生脓毒症分为脓毒症组(n=112)和非脓毒症组(n=112)。患者入院后完善相关检查,查阅病例资料调查并统计两组APACHEⅡ、急性肾损失、MODS、合并慢性病、意识障碍、平均动脉压以及电解质紊乱情况,对上述危险因素进行单因素及多因素Logistic回归分析。结果 224例成人烧伤患者中死亡患者37例,占16.52%。其中,脓毒症组死亡31例,非脓毒症组死亡6例。单因素及多因素Logistic分析结果表明:成人烧伤脓毒症患者死亡率与APACHEⅡ评分、MODS、合并慢性病、急性肾损伤、意识障碍及电解质差异有统计学意义(P <0.05)。结论成人烧伤脓毒症患者死亡率相对较高,危险因素相对较多,应及时针对上述危险因素制定相应的措施干预,降低临床死亡率。

Objective To explore Logistic regression analysis of risk factors for death in adult patients with burned sepsis. Methods Two hundred and twenty-four adult patients with burned sepsis who were admitted and treated in our hospital from July 2010 to July 2016 were selected as research objects.According to whether patients developed sepsis,they were divided into the sepsis group(n=112)and the non-sepsis group(n=112).After admission,relevant examinations of the patients were improved.Case data were reviewed for investigation and statistics of APACHE Ⅱ,acute renal injury,MODS,complicated with chronic diseases,disturbance of consciousness,mean arterial pressure and electrolyte disturbance in the two groups.Univariate and multivariate Logistic regression analysis was performed for the above risk factors. Results Of the 224 adult burn patients,37 died,accounting for 16.52%.Among them,31 cases died in the sepsis group and 6 cases died in the non-sepsis group.Univariate and multivariate Logistic analysis showed that the mortality of adult patients with burn sepsis was statistically significant relations with APACHE Ⅱ score,MODS,complicated with chronic diseases,acute renal injury,disturbance of consciousness and electrolyte disturbance(P < 0.05). Conclusion The mortality rate of adult patients with burn sepsis is relatively high and the risk factors are relatively high.It is necessary to timely formulate corresponding measures for the above-mentioned risk factors to reduce clinical mortality.