纳米碳淋巴结示踪技术在精准治疗胰体尾部恶性肿瘤中的应用研究

APPLICATION OF NANO-CARBON LYMPH NODE TRACING TECHNIQUE IN ACCURATE TREATMENT OF MALIGNANT TUMORS OF PANCREATIC BODY AND TAIL

目的探讨在胰体尾部肿瘤切除术中清扫淋巴结的方法。方法选取31例胰体尾部恶性肿瘤患者。将其随机分为实验组(17例)和对照组(14例)。两组均行RAMPS手术,实验组术中应用纳米碳示踪技术指导淋巴结清扫;对照组行常规淋巴结清扫。观察比较两组术后淋巴结清扫数目,随访了解患者预后情况等。结果清扫淋巴结数量:实验组共清扫淋巴结230枚,平均(13.53±1.84)枚;对照组共清扫95枚,平均(6.79±1.23)枚;两组比较有统计学意义(t=11.7,P<0.01)。实验组:黑染淋巴结中阳性率为38.41%,未黑染淋巴结中阳性率为17.39%,二者比较具统计学意义(χ~2=10.63,P<0.01)。结论纳米碳淋巴结示踪技术能精准指导手术操作,改善患者预后。

Objective To investigate the method of lymph node dissection in tumor resection of the pancreas. Methods Thirty-one patients with malignant tumors of the tail of the pancreas were selected. They were randomly divided into an experimental group (17 cases) and a control group (14 cases). Both groups underwent RAMPS surgery. The experimental group used nano-carbon tracer technique to guide lymph node dissection. The control group underwent routine lymph node dissection. The number of postoperative lymph node dissections in the two groups were observed and compared, and patients were followed up to investigate the prognosis. Results The number of lymph nodes was cleaned: 230 lymph nodes were cleaned in the experimental group, with an average of(13.53±1.84). In the control group, 95 were cleaned, with an average of(6.79±1.23).The results from two groups were statistically significant( t =11.7, P <0.01). In the experimental group, the positive rate was 38.41% in black-stained lymph nodes and 17.39% in un-stained lymph nodes. The results from two groups were statistically significant(χ^2=10.63, P <0.01). Conclusion Nano-carbon lymph node tracing technology can accurately guide the operation and improve the prognosis of patients.