小剂量糖皮质激素布地奈德吸入治疗支气管哮喘中的应用价值

Application Value of Low-dose Glucocorticoid Budesonide Inhalation in the Treatment of Bronchial Asthma

目的探讨小剂量糖皮质激素布地奈德吸入治疗支气管哮喘中的价值。方法选取一般资料为2015年1月—2018年10月该院的支气管哮喘患者500例,将患者随机分为两组,对照组245例(采取常规治疗),研究组255例(给予小剂量糖皮质激素布地奈德吸入治疗),比较两组的治疗效果。结果研究组治疗有效率为94.12%(240/255),对照组为85.31%(209/245),差异有统计学意义(P<0.05)。治疗后研究组FEV1(一秒用力呼气容积)、气道传导率(Gaw)、气道阻力(Raw)跟对照组相比,较后者更优(P<0.05)。研究组的肺部哮鸣音、喘憋减轻时间、住院时间跟对照组相比,较后者更短(P<0.05)。结论对于支气管哮喘患者,采取小剂量糖皮质激素布地奈德吸入治疗,可有效改善患者的临床症状和肺功能。

Objective To investigate the value of low-dose glucocorticoid budesonide inhalation in the treatment of bronchial asthma.Methods A total of 500 patients with bronchial asthma in our hospital from January 2015 to October 2018 were enrolled.The patients were randomly divided into two groups,245 in the control group(conventional treatment)and 255 in the study group(small dose of sugar corticosteroid budesonide inhalation treatment)compared the therapeutic effects of the two groups.Results The effective rate of the study group was 94.12%(240/255),and that of the control group was 85.31%(209/245),the difference was statistically significant(P<0.05).After treatment,the study group FEV1(forced expiratory volume in one second),airway conductance(Gaw),and airway resistance(Raw)were superior to the control group(P<0.05).The lung wheezing,wheezing reduction time,and hospital stay of the study group were shorter than those of the control group(P<0.05).Conclusion For patients with bronchial asthma,low-dose glucocorticoid budesonide inhalation therapy can effectively improve the clinical symptoms and lung function of patients.