鼻塞式持续气道正压通气联合沐舒坦治疗小儿重症肺炎的效果

Effect of nasal continuous positive airway pressure combined with Mucosolvan in the treatment of severe pneumonia in children

目的分析鼻塞式持续气道正压通气联合沐舒坦治疗小儿重症肺炎的效果。方法选取2016年7月～2018年7月我院儿科收治的30例小儿重症肺炎者作为研究对象,以电脑随机分组方式分为对照组、试验组,每组各15例。两组均予以综合治疗,对照组加用面罩给氧治疗,试验组加用鼻塞式持续气道正压通气联合沐舒坦治疗。比较两组的血气分析指标、症状消失时间、临床疗效、并发症发生情况。结果治疗后,试验组患者的血氧饱和度(SaO_2)、血氧分压(PaO_2)高于对照组,血二氧化碳分压(PaCO_2)低于对照组,差异有统计学意义(P<0.05)。试验组的发绀、呼吸困难、肺部啰音的症状消失时间均短于对照组,差异有统计学意义(P<0.05)。试验组的治疗总有效率(100.00%)显著高于对照组(66.67%),差异有统计学意义(P<0.05)。试验组的并发症总发生率(26.67%)略低于对照组(40.00%),但差异无统计学意义(P>0.05)。结论鼻塞式持续气道正压通气联合沐舒坦治疗小儿重症肺炎的效果可靠,能够保证安全性,具有推广价值。

Objective To analyze the effect of nasal continuous positive airway pressure combined with Mucosolvan in the treatment of severe pneumonia in children.Methods Thirty children with severe pneumonia admitted to our hospital from July 2016 to July 2018 were selected as study objects.They were divided into the control group and the experimental group by using computer randomization grouping method,with 15 cases in each group.Both groups were treated with comprehensive treatment.In the control group,mask oxygen inhalation was used,while in the experimental group,nasal continuous positive airway pressure combined with Mucosolvan was adopted.The blood gas analysis parameters,time of symptoms disappearance,clinical efficacy,and occurrence of complications were compared in between the two groups.Results After treatment,SaO2 and PaO2 in the experimental group were higher than those in the control group,and PaCO2 was lower than that of the control group,and the differences were statistically significant(P<0.05).The time of symptoms disappearance such as cyanosis,dyspnea,and pulmonary rale in the experimental group was shorter than that in the control group,and the differences were statistically significant(P<0.05).The total effectiveness rate of treatment in the experimental group was 100.00% ,which was much obviously higher than that in the control group accounting for 66.67% ,and the difference was statistically significant(P<0.05).The total incidence of complications in the experimental group was 26.67% ,which was slightly lower than that in the control group accounting for 40.00% ,but without significance(P>0.05).Conclusion Nasal continuous positive airway pressure combined with Mucosolvan is effective in the treatment of severe pneumonia in children,and it can ensure safety and has a promotion value.