手卫生在控制肺炎患儿医院感染轮状病毒肠炎中的效果及对患儿炎性反应的影响

Effect of hand hygiene in control of nosocomial Rotavirus enteritis in children with pneumonia and its influence on inflammatory reaction

目的探讨手卫生在控制肺炎患儿医院感染轮状病毒肠炎中的效果及对患儿炎性反应的影响。方法选取2017年4月～2018年5月珠海市中西医结合医院收治的肺炎患儿120例作为研究对象,按照随机数字表分为对照组(n=60)和观察组(n=60)。对照组给予常规护理干预,观察组在对照组基础上联合手卫生干预。护理1个月后,评估患者的护理效果,比较两组的轮状病毒肠炎发生率及炎性反应指标。结果两组干预后1、2周的轮状病毒肠炎发生率比较,差异无统计学意义(P>0.05);两组干预后3、4周的轮状病毒肠炎发生率均高于1周(P<0.05);观察组干预后3、4周的轮状病毒肠炎发生率均低于对照组(P<0.05)。观察组干预后1个月的白细胞介素-4(IL-4)、IL-6、IL-8、肿瘤坏死因子-α(TNF-α)水平低于对照组(P<0.05)。结论加强肺炎患儿手卫生控制有助于降低医院轮状病毒肠炎感染率,能减轻患儿的炎性反应,值得推广应用。

Objective To investigate the effect of hand hygiene in control of nosocomial Rotavirus enteritis in children with pneumonia and its influence on inflammatory reaction.Methods A total of 120 children with pneumonia treated in Zhuhai City Hospital of Integrated Traditional Chinese and Western Medicine from April 2017 to May 2018 were selected as study objects.According to the random number table,they were divided into the control group(n=60)and observation group(n=60).The control group was given routine nursing intervention,while the observation group was combined with hand hygiene intervention on the basis of the control group.After one month of nursing,the nursing effect of patients was evaluated,and the incidence of Rotavirus enteritis and inflammatory reaction index were compared between the two groups.Results There was no significant difference in the incidence of Rotavirus enteritis between the two groups at 1 and 2 weeks after intervention(P>0.05);the incidence of Rotavirus enteritis at 3 and 4 weeks after intervention was higher than that at 1 week(P<0.05);the incidence of Rotavirus enteritis at 3 and 4 weeks after intervention in the observation group was lower than that in the control group(P<0.05).The levels of interleukin-4(IL-4),IL-6,IL-8 and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group one month after intervention(P<0.05).Conclusion Strengthening hand hygiene control of children with pneumonia is helpful to reduce the infection rate of Rotavirus enteritis in hospitals and reduce the inflammatory reaction of children,which is worthy of popularization and application.