静脉血栓形成时间推断的法医学研究进展

Research Progress on Age Determination of Venous Thrombosis in Forensic Medicine

静脉血栓脱落导致的肺血栓栓塞症(pulmonary thromboembolism,PTE)是法医学实践中常见的猝死原因之一。对于一些机体受创伤后因PTE死亡,或是以非血栓相关疾病收治入院期间因PTE死亡的案例,需要法医病理学工作者分析创伤或医疗行为与静脉血栓发生之间的时间顺序,进而分析其因果关系。本文总结了法医学领域有关静脉血栓形成时间推断的研究成果,并对今后的研究进行了简要展望,以期为PTE的法医学鉴定提供参考,并为后续的研究指引方向。

Pulmonary thromboembolism (PTE),which is caused by detachment of venous thrombosis, is a common cause of sudden death in forensic practice. In the cases which die of PTE after trauma or die of PTE during non-thrombosis disease hospitalization,forensic pathologists are required to analyze the time sequence between trauma or medical practice and venous thrombosis,and then analyze their causal relationship. This review summarizes the history of thrombus age estimation and recent advances in forensic medicine,and then gives a brief outlook for future research to provide reference for forensic identification of PTE and guide follow-up studies.