实时三维超声心动图评价左室心肌致密化不全患儿左室收缩功能及同步性

Evaluation of left ventricular systolic function and synchrony in children with left ventricular noncompaction by real-time three-dimensional echocardiography

目的应用实时三维超声心动图(RT-3DE)技术评价左室心肌致密化不全(LVNC)患儿左室收缩功能及同步性。方法选取34例LVNC患儿,按射血分数(EF)测值分为EF正常组(EF≥55%,25例)和EF减低组(EF<55%,9例),另选20例与其年龄、身高和体质量相匹配的健康儿童作为正常对照组。应用RT-3DE自动输出时间-容积曲线,获得收缩同步性参数:16节段、12节段和6节段达到最小容积时间的标准差、最大差值及两者校正值(Tmsv-SD、Tmsv-Dif和Tmsv-SD%、Tmsv-Dif%),并比较各组上述参数的差异。结果 EF正常组16节段和12节段的Tmsv-SD、Tmsv-Dif、Tmsv-SD%、Tmsv-Dif%与正常对照组比较,差异均有统计学意义(均P<0.05),而6节段各参数与正常对照组比较差异均无统计学意义;EF减低组16节段、12节段和6节段的Tmsv-SD、Tmsv-Dif、Tmsv-SD%、Tmsv-Dif%与正常对照组比较,差异均有统计学意义(均P<0.05);EF正常组16节段的Tmsv-SD、Tmsv-Dif、Tmsv-SD%、Tmsv-Dif%与EF减低组比较,差异均有统计学意义(均P<0.05)。结论应用RT-3DE技术可对LVNC患儿左室收缩功能及同步性进行早期评估,有一定的临床价值。

Objective To evaluate left ventricular systolic function and systolic synchrony in children with left ventricular noncompaction(LVNC) by real-time three-dimensional echocardiography(RT-3 DE).Methods Thirty-four children with LVNC were enrolled.They were divided into EF normal group(EF≥55%,25 cases)and EF reduction group(EF<55%,9 cases).20 healthy children who were consistent with the age,height and weight of the experimental group were selected as the normal control group.The time-volume curve was automatically displayed by RT-3 DE to obtain the systolic synchrony parameters of 16 segments,12 segments and 6 segments(Tmsv-SD,Tmsv-Dif,Tmsv-SD%,Tmsv-Dif%),the differece of above parameters were compared.Results Compared with the normal control group,the differences of Tmsv-SD,Tmsv-Dif,Tmsv-SD% and Tmsv-Dif% in the EF normal group were statistically significant in 16 and 12 segments(all P<0.05),while not significant in 6 segments.Compared with the normal control group,the differences of Tmsv-SD,Tmsv-Dif,Tmsv-SD% and Tmsv-Dif% in 16 segments,12 segments and 6 segments in the EF reduction group were statistically significant(all P<0.05).By comparing the EF normal group with the EF reduction group,Tmsv-SD,Tmsv-Dif,Tmsv-SD% and Tmsv-Dif% in 16 segments were significant difference(all P<0.05).Conclusion RT-3DE technique can evaluate the systolic function and systolic synchrony of LVNC in early stage,which has a certain clinical value.