COOK球囊联合催产素与欣普贝生用于足月妊娠促宫颈成熟及引产的效果评价

Evaluation of effect of COOK balloon combined with oxytocin and dinoprostone on cervical ripening and induction of labor in term pregnancy

①目的比较孕足月无产兆孕妇采用COOK球囊联合催产素与欣普贝生引产的效果,探讨更安全有效的引产方法。②方法选取在华北理工大学附属医院住院的孕37~42周的孕妇,根据引产方法的不同分为COOK球囊组70例,欣普贝生组85例,进行促宫颈成熟效果、取出指征、产程进展和母婴结局的比较。③结果两组引产后宫颈评分均明显提高,平均均提高2分以上,经检验,差异均有统计学意义(P<0.05)。但两组孕妇促宫颈成熟的有效率在80%以上,两者相比,差异无统计学意义(P>0.05);欣普贝生引产过程中胎心异常、子宫过度刺激、发热所占比例高,经检验,胎心异常差异存在统计学意义(P<0.05),余无统计学意义(P>0.05)。COOK球囊组干预到临产时间,明显长于欣普贝生组,经检验,差异有统计学意义(P<0.05),但总产程、第一产程、第二产程,经检验,差异均无统计学意义(P>0.05);两组的剖宫产率,经检验,差异无统计意义(P>0.05),而欣普贝生组的24小时分娩率明显高于COOK球囊组,差异有统计学意义(P<0.05)。两组引产方法的分娩结局,经检验,差异无统计学意义(P>0.05)。④结论欣普贝生诱导宫颈成熟度较好,但需注意子宫过度刺激造成的影响。COOK球囊引比较温和,适合妊娠合并症孕妇。

Objective To compare the effect of COOK balloon combined with oxytocinand Dinoprostone on the induction of labor.To explore the appropriate induction of labor. Methods Pregnantaged from 37 to 42 weeks were enrolled in the North China University of Science and Technology Affiliated Hospital.According to the different methods of induction,It was divided into the COOK balloon group(70 cases),Dinoprostone group(85 cases),the comparison was made to improve cervical ripening,removal of indications,labor progress and maternal and child outcomes. Results The cervical scores of the two groups were significantly increased after induction of labor,and the average scores were increased by more than 2 points.After the test,the differences were statistically significant( P < 0.05 ).However,the effective rate of cervical ripening in the two groups of pregnant women was above 80%.There was no significant difference between the two groups ( P > 0.05 ).The incidence of fetal heart abnormality,uterine hyperstimulation and fever during the induction of labor was high.After testing,the abnormal fetal heart rate was statistically significant( P < 0.05 ),and the rest was not statistically significant( P > 0.05 ).The COOK balloon group intervention time was significantly longer than that of the Dinoprostone group.The difference was statistically significant( P < 0.05 ),but the total labor,first labor,and second stage of labor were tested.The difference was no statistically significant( P > 0.05 ).The cesarean section rate of the two groups was not statistically significant ( P > 0.05 ),while the 24-hour delivery rate of the Dinoprostone group was significantly higher than that of the COOK balloon group( P < 0.05 ).The outcome of delivery in the two groups of induction methods was not statistically significant( P > 0.05 ). Conclusion Dinoprostoneinduced cervical maturity is better,but pay attention to the impact of labor caused by too fast.The effect of COOK balloon and oxytocin at the same time is better than the latter,it is worth in the labor promotion.