腹腔镜下全子宫切除对患者性激素水平及术后生活质量的影响

Influence of laparoscopic total hysterectomy on the sex hormone and quality of life of patients with hysteromyoma

目的探讨腹腔镜下全子宫切除对患者性激素水平及术后生活质量的影响。方法选取2015年1月至2017年5月渭南市妇幼保健院诊治的140例子宫肌瘤患者作为研究对象。按随机数字表法将其分为研究组与对照组,每组70例。对照组患者采用常规开腹子宫切除术治疗,研究组患者采用腹腔镜下全子宫切除术治疗,治疗后比较两组患者一般指标、性激素水平、生活质量与性生活质量。结果研究组患者手术时间、术中出血量、住院时间及肛门排气时间均较对照组短,差异均具有统计学意义(均P<0.05)。术前两组患者性激素水平较差异无统计学意义(P>0.05)。术后研究组患者FSH和LH水平均低于对照组,E2水平较对照组高,但差异均无统计学意义(均P>0.05)。术前两组患者生活质量比较差异无统计学意义(均P>0.05)。术后研究组患者躯体疼痛评分较对照组低,其他维度评分均高于对照组,差异均具有统计学意义(均P<0.05)。术前两组患者性生活质量评分比较差异无统计学意义(P>0.05)。术后研究组性生活质量各维度评分均较对照组高,差异均具有统计学意义(均P<0.05)。结论与开腹子宫切除术相比,腹腔镜下全子宫切除术对患者性激素水平影响相似,但对生活质量及性生活质量改善效果更好,且具有创伤小、术后恢复快的特点。

ObjectiveTo investigate the influence of laparoscopic total hysterectomy (LTH) on the sex hormone and quality of life of patients with hysteromyoma.Methods140 patients with hysteromyoma in our hospital from January 2015 to May 2017 were selected and randomly divided into control group and research group.Patients in the control group were treated with conventional open hysterectomy and patients in the research group were treated by LTH. The general data, sex hormone level, quality of life and quality of sexuallife between the two group were compared. ResultsThe operation time, amount of intraoperative blood loss, time of hospitalization and anus exhaust time of research group were shorter than those of control group, with statistically significant differences (all P<0.05). There was no statistically significant difference in sex hormone levels between the two groups before operation(P>0.05).After operation, the levels of FSH and LH in the research group were lower than those in the control group, while levels of E2 were higher than those of control group, without statistically significant differences (all P>0.05).Before operation, there was no statistically significant difference in quality of life between the two groups (all P>0.05).After operation,the scores of somatic pain in research group were lower than those in control group, and the scores of other dimensions were higher than those in control group, all with statistically significant differences (all P<0.05).Before operation, difference in quality ofsexual life between the two group was notstatistically significant (P>0.05).After operation, the scores of quality ofsexual life in research group were all higher than those of control group, with statistically significant differences(all P<0.05).Conclusions Compared with conventional open hysterectomy, LTH has similar effect on sex hormone but better improvement on quality of life and sex life, with small trauma and quick recovery.