重症肺炎的抗菌药物降阶梯治疗策略与万古霉素的临床应用

Severe Pneumonia Antibacterial Drugs Down Stairs Treatment Strategies and the Clinical Application of Vancomycin

目的对抗菌药物降阶梯治疗策略联合万古霉素在治疗重症肺炎患者中的效果进行分析。方法选取医院收治的重症肺炎患者68例,按照治疗方法划分为对照组与观察组各34例,对照组给予传统治疗方法,观察组用抗菌药物降阶梯治疗与万古霉素联合应用方法,对两组患者感染控制时间、感染控制率进行比较。结果感染控制时间,观察组治疗(7.5±2.6)d少于对照组(19.2±4.6)d,差异显著(P <0.05)。感染控制率观察组88.24%(30/34)高于对照组55.88%(19/34),差异显著(P <0.05),有统计学意义。结论抗菌药物降阶梯治疗策略联合万古霉素应用于重症肺炎患者治疗中,对减少感染率控制时间、提高治疗效果可发挥重要作用,应在临床实践中进行推广。

Objective The antimicrobial drugs down stairs treatment strategies combined effect of vancomycin in the treatment of patients with severe pneumonia were analyzed. Methods To choose the hospital treated 68 cases of patients with severe pneumonia, according to the treatment is divided into control group and observation group, 34 cases in the control group given conventional treatment, observation group used antibacterial drugs down stairs treatment with vancomycin application methods, infection control in patients with two groups of time, infection control is used in the comparison. Results The infection control time, observation group treatment(7.5±2.6)d less than the control group(19.2±4.6)d, significant difference(P <0.05). Infection control group 88.24%(30/34)is higher than the control group 55.88%(19/34), the significant difference(P <0.05), with statistical significance. Conclusion The antibacterial drugs down stairs joint vancomycin treatment strategies applied in the treatment of patients with severe pneumonia, to reduce the infection rate control time and improve the effect of treatment can play an important role, should be popularized in clinical practice.