老年2型糖尿病患者基础胰岛素门诊治疗的临床观察

Elderly patients with type 2 diabetes mellitus insulin outpatient treatment clinical observation

目的观察老年2型糖尿病患者基础胰岛素门诊治疗的临床疗效。方法选取本院糖尿病门诊口服降糖药治疗不佳的90例老年2型糖尿病患者作为观察对象,均分为观察组和对照组,两组均服用格列美脲,观察组皮下注射甘精胰岛素,对照组皮下注射地特胰岛素,治疗周期为6个月。结果治疗后,两组组内比较FBG、2hPBG、HbA1c均明显低于治疗前(P<0.05);治疗后,对照组FBG明显的低于观察组(P<0.05),两组2hPBG、HbA1c比较均无显著性差异(P>0.05);两组低血糖发生率无显著性差异(P>0.05),对照组胰岛素用量明显的低于观察组(P<0.05)。结论口服降糖药控制不佳的老年2型糖尿病患者,采用格列美脲联合甘精胰岛素或地特胰岛素治疗均能有效控制血糖,安全性好,后者胰岛素用量更少。

Objective Observation of elderly patients with type 2 diabetes mellitus insulin outpatient treatment clinical curative effect. Methods Choose our poor oral medications to treat 90 cases of diabetes clinics in elderly patients with type 2 diabetes as research object, were divided into observation group and control group, Two groups are taking Glenn beauty urea, observation group of subcutaneous insulin injection, the control group in subcutaneous injection of insulin, treatment period is 6 months. Results After treatment, the comparison of FBG, 2 HPBG, HbA1c within two way were significantly lower than before treatment (P < 0.05);After treatment, the control of FBG obviously is lower than the observation group (P < 0.05), two groups of 2 HPBG, HbA1c comparison there was no significant difference (P > 0.05);Two groups the incidence of hypoglycaemia there was no significant difference (P > 0.05), obviously lower than control group insulin group (P < 0.05). Conclusion Oral medications poorly controlled in elderly patients with type 2 diabetes, Glenn beauty urea joint insulin or to insulin treatment can effectively control blood sugar, good security, the latter less dosage of insulin.