中西医结合治疗慢性乙肝的临床观察

Clinical Observation on Treatment of Chronic Hepatitis B with Integrative Medicine Therapy

目的探究应用中西医结合疗法对慢性乙肝患者进行治疗的临床效果。方法选取2016年10月～2017年11月于我院进行诊治的慢性乙肝患者86例,随机分为常规组与观察组,每组43例。常规组患者采用拉米夫定和肌苷片进行治疗;观察组患者在常规组的治疗基础上添加自拟疏肝健脾方剂进行治疗。对比两组患者治疗后的谷丙转氨酶(ALT)、谷草转氨酶(AST)、总胆红素(TBIL)等肝功能指数及治疗效果。结果观察组TP为(67.62±3.17)g/L,高于常规组的(61.57±3.29)g/L,观察组AST(47.88±18.97)U/L、ALT(61.29±27.77)U/L和TBIL(27.33±9.28)μmol/L分别低于常规组的(47.88±18.97)U/L、(53.57±26.64)U/L、(38.59±9.77)μmol/L,差异均有统计学意义(P<0.05)。观察组治疗的总有效率为86.05%,高于常规组的65.12%,差异有统计学意义(P<0.05)。结论中西医结合治疗慢性乙肝疗效显著,可有效促进患者肝功能的恢复,提高疗效,值得临床借鉴。

Objective To explore the clinical effect of the treatment of chronic hepatitis B patients with integrative medicine therapy.Methods 86 patients with chronic hepatitis B who were treated in our hospital from October 2016 to November 2017 were randomly divided into the conventional group and the observation group, with 43 cases in each group. The patients in the conventional group were treated with lamivudine and inosine tablets;the patients in the observation group were treated with the traditional Shugan Jianpi Recipe on the basis of the treatment of the conventional group.The liver function indexes and therapeutic effects of alanine aminotransferase (ALT), aspartate aminotransferase(AST),and total bilirubin (TBIL) were compared between the two groups.Results The TP of the observation group was (67.62±3.17) g/L, which was higher than that of the conventional group (61.57±3.29) g/L, and the observed group AST (47.88±18.97) U/L, ALT (61.29±27.77) U/L and TBIL (27.33±9.28)μmol/L was lower than that of the conventional group (47.88±18.97 U/L,(53.57±26.64) U/L,(38.59±9.77)μmol/L, the difference was statistically significant (P<0.05). The total effective rate of the observation group was 86.05%, which was higher than that of the conventional group 65.12%,the difference was statistically significant (P<0.05).Conclusion The combination of traditional Chinese medicine and western medicine has significant curative effect on chronic hepatitis B, which can effectively promote the recovery of liver function and improve the curative effect. It is worthy of clinical reference.