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右美托咪定联合丙泊酚在脑功能区神经胶质瘤治疗中的应用

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摘要 右美托咪定是新型高选择性肾上腺素能受体激动剂,可在蓝斑核发挥作用,从而发挥其镇静作用。其机理在于激动蓝斑核α_2受体,抑制NE释放,促进抑制性神经递质释放从而产生拟睡眠状态的镇静、镇痛作用。脑功能区神经胶质瘤因其复杂的解剖结构在神经外科手术治疗中往往无法达到彻底切除的效果,且易并发失语、肢体瘫痪等并发症,近年来随着右美托咪定的出现,唤醒开颅手术治疗功能区神经胶质瘤技术逐渐成为临床应用热点。本文主要论述右美托咪定联合丙泊酚在脑功能区神经胶质瘤治疗中的应用。
出处 《中国处方药》 2019年第5期18-19,共2页 Journal of China Prescription Drug
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